Intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide.
Journal of Bioscience and Bioengineering(2013)
摘要
This study focused on the intracellular observation of nanocarriers modified with a mitochondrial targeting signal peptide (MTS). The nanocarriers showed an efficient cellular uptake, and the MTS had a positive effect on their mitochondrial targeting. This is the first report of an intracellular observation of nanocarriers modified with MTS.
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关键词
Mitochondria,Mitochondrial drug delivery,Mitochondrial targeting signal peptide (MTS),MITO-Porter,Nanocarriers,Nanotechnology
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