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Accelerated lipid-induced atherogenesis in galectin-3-deficient mice: role of lipoxidation via receptor-mediated mechanisms.

Carla Iacobini,Stefano Menini,Carlo Ricci,Angela Scipioni,Viola Sansoni,Samantha Cordone,Maurizio Taurino,Matteo Serino,Giuseppe Marano,Massimo Federici,Flavia Pricci,Giuseppe Pugliese

Arteriosclerosis, thrombosis, and vascular biology（2009）

Cited 77|Views4
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Abstract
These data suggest a unique protective role for galectin-3 in the uptake and effective removal of modified lipoproteins, with concurrent downregulation of proinflammatory pathways responsible for atherosclerosis initiation and progression.
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Key words
atherosclerosis,inflammation,advanced lipoxidation end products,galectin-3,RAGE
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