Preparation and Optimization of New 4-(Morpholin-4-yl)-(6-oxo-1,6-dihydropyrimidin-2-yl)amide Derivatives As PI3Kβ Inhibitors
Victor Certal,Frank Halley,Angela Virone-Oddos,Fabienne Thompson,Bruno Filoche-Romme,Youssef El-Ahmad,Jean-Christophe Carry,Cecile Delorme,Andreas Karlsson,Pierre-Yves Abecassis,Loic Vincent,Helene Bonnevaux,Jean-Paul Nicolas,Renaud Morales,Nadine Michot,Isabelle Vade,Audrey Louboutin,Sebastien Perron,Gilles Doerflinger, Bernadette Tric, Sylvie Monget, Christoph Lengauer, Laurent Schio Bioorganic & medicinal chemistry letters（2012）
关键词
Pyrimidone anilide,Kinase inhibitor,PI3K beta,pAkt,PTEN
AI 理解论文
溯源树
样例
