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Structure- and Property-Based Design of Aminooxazoline Xanthenes As Selective, Orally Efficacious, and Cns Penetrable Bace Inhibitors for the Treatment of Alzheimer'S Disease

Hongbing Huang,Daniel S. La,Alan C. Cheng,Douglas A. Whittington,Vinod F. Patel,Kui Chen,Thomas A. Dineen,Oleg Epstein,Russell Graceffa,Dean Hickman,Y. -H. Kiang,Steven Louie,Yi Luo, Robert C. Wahl,Paul H. Wen,Stephen Wood,Robert T. Fremeau

Journal of medicinal chemistry（2012）

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