Discovery of azetidinone acids as conformationally-constrained dual PPARalpha/gamma agonists.
Wei Wang,Pratik Devasthale,Dennis Farrelly,Liqun Gu,Thomas Harrity,Michael Cap,Cuixia Chu,Lori Kunselman,Nathan Morgan,Randy Ponticiello,Rachel Zebo,Litao Zhang,Kenneth Locke,Jonathan Lippy,Kevin O'Malley,Vinayak Hosagrahara,Lisa Zhang,Pathanjali Kadiyala,Chiehying Chang,Jodi Muckelbauer,Arthur M Doweyko,Robert Zahler,Denis Ryono,Narayanan Hariharan,Peter T W Cheng BIOORGANIC & MEDICINAL CHEMISTRY LETTERS（2008）
关键词
PPAR, dual PPAR alpha/gamma agonists, antidiabetic azetidinones, boronic acid coupling, conformational constraint
AI 理解论文
溯源树
样例
