Quantification of duodenogastric reflux in symptomatic patients with choledochoduodenostomy using intravenous continuous perfusion of 99mTc-HIDA as duodenal marker]

The purpose of the present study was to determine whether the measurement of intravenously administered 99mTc-HIDA in samples of gastric juice can be used as a reliable marker of duodenogastric reflux. Ten normal volunteers and 10 patients with a laterolateral choledocho-duodenostomy complaining of dyspepsia but no biliary pain, were given a continuous i.v. infusión of 99mTc-HIDA. The isotope concentration was then measured in samples of gastric juice. We found that duodeno-gastric reflux was significantly higher (p less than 0.001) in patients with choledochoduodenostomy and dyspepsia than in normal volunteers.