Novel 4,4-disubstituted piperidine-based C-C chemokine receptor-5 inhibitors with high potency against human immunodeficiency virus-1 and an improved human ether-a-go-go related gene (hERG) profile.

Wieslaw M Kazmierski,Don L Anderson,Christopher Aquino,Brian A Chauder,Maosheng Duan,Robert Ferris,Terrence Kenakin,Cecilia S Koble,Dan G Lang,Maggie S McIntyre,Jennifer Peckham,Christian Watson,Pat Wheelan,Andrew Spaltenstein,Mary B Wire,Angilique Svolto,Michael Youngman

JOURNAL OF MEDICINAL CHEMISTRY（2011）

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inhibitors,piperidine-based,ether-a-go-go

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