Intramedullary tuberculoma in a patient with human immunodeficiency virus infection and disseminated multidrug-resistant tuberculosis: Case report

Intramedullary tuberculomas are extremely rare, being present in approximately 2 of every 100,000 cases of tuberculosis and 2 of every 1000 cases of tuberculosis of the central nervous system.‘-* Infection with human immunodeficiency virus (HIV) increases the risk of tuberculosis, which may occur at any stage of immunodeficiency. Extrapulmonary disease is more common in patients with HIV infection.5-s The authors believe that the following is the first report of an intramedullary tuberculoma, associated with HIV infection, in a patient with disseminated multidrug-resistant tuberculosis. The patient’s neurologic condition improved after an antituberculosis retreatment regimen that included isoniazid, pyrazinamide, amikacin, and ciprofloxacin.