[Paroxysmal nocturnal hemoglobinuria therapy with eculizumab: Spanish experience].
Medicina clinica(2011)
摘要
Eculizumab controls effectively hemolysis and greatly improves clinical symptoms. The drug is safe and well tolerated, without significant adverse effects except meningococcal infection. Patients with suboptimal response to treatment must be assessed for bone marrow insufficiency and extravascular haemolysis.
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