Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: from Hit to Clinic
Mathieu Pizzonero,Sonia Dupont,Marielle Babel,Stephane Beaumont,Natacha Bienvenu,Roland Blanque,Laetitia Cherel,Thierry Christophe,Benedetta Crescenzi,Elsa De Lemos,Philippe Delerive,Pierre Deprez,Steve De Vos,Fatoumata Djata,Stephen Fletcher,Sabrina Kopiejewski,Christelle L'Ebraly,Jean-Michel Lefrancois,Stephanie Lavazais,Murielle Manioc,Luc Nelles,Line Oste,Denis Polancec,Vanessa Quenehen,Florilene Soulas,Nicolas Triballeau,Ellen M. van der Aar,Nick Vandeghinste,Emanuelle Wakselman,Reginald Brys,Laurent Saniere Journal of medicinal chemistry(2014)
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