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Highly Efficient Deletion of FUT8 in CHO Cell Lines Using Zinc‐finger Nucleases Yields Cells That Produce Completely Nonfucosylated Antibodies

Biotechnology and Bioengineering(2010)

引用 140|浏览27
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关键词
homologous recombination,antibody-dependent cellular cytotoxicity,biopharmaceutical,fucosylation,monoclonal antibody
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