Substituted isoxazole analogs of farnesoid X receptor (FXR) agonist GW4064

Jonathan Y. Bass,Richard D. Caldwell,Justin A. Caravella,Lihong Chen,Katrina L. Creech,David N. Deaton,Kevin P. Madauss,Harry B. Marr,Robert B. McFadyen,Aaron B. Miller,Derek J. Parks,Dan Todd,Shawn P. Williams,G. Bruce Wisely

Bioorganic & Medicinal Chemistry Letters（2009）

引用 56|浏览55

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关键词

Farnesoid X receptor agonist,FXR,Nuclear receptor modulator,FXR X-ray co-crystal structure,GW4064,Bile acid receptor,NR1H4

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