Synthesis and Derivatization of 3-Perfluoroalkyl-Substituted 7-Azaindoles

Hartmut Schirok,Santiago Figueroa-Pérez,Michael Thutewohl,Holger Paulsen,Walter Kroh,Dagmar Klewer

SYNTHESIS-STUTTGART（2007）

引用 20|浏览13

暂无评分

摘要

An expedient large-scale synthesis of 3-perfluoroalkyl-7-azaindoles starting from 2-fluoropyridine is presented. The activation as 6-chloro-4-nitro derivative allows the further derivatization by nucleophilic aromatic substitution in the 4-position.

查看译文

关键词

7-azaindoles,cyclizations,multicomponent reactions,directed ortho metalation,fluorine

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要