Design, synthesis and structure–activity relationships of novel biarylamine-based Met kinase inhibitors
Bioorganic & Medicinal Chemistry Letters（2010）
Abstract
Biarylamine-based inhibitors of Met kinase have been identified. Compound 9b demonstrated potent in vivo antitumor activity in the GTL-16 human tumor xenograft model.
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Key words
c-Met kinase inhibitor,Kinase inhibitor,HGFR inhibitor,Met kinase
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