Preparation of Neplanocin-a from D-ribose and by a Chemoenzymic Method

JM HILL,EJ HUTCHINSON, DM LEGRAND,SM ROBERTS,AJ THORPE,NJ TURNER

Journal of the Chemical Society Perkin transactions I/Journal of the Chemical Society Perkin transactions I（1994）

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摘要

The carboxylic acid 6 was converted into the amine 13 en route to neplanocin-A 9. The same enantiomer of the amine 13 was made from D-ribose in a 13-step synthesis.

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