Pharmacokinetics of oral gabapentin in greyhound dogs.
The Veterinary Journal(2011)
摘要
The purpose of this study was to assess the pharmacokinetics of gabapentin in healthy greyhound dogs after single oral doses targeted at 10 and 20mg/kg PO. Six healthy greyhounds were enrolled (3 males, 3 females). Blood was obtained at predetermined times for the measurement of gabapentin plasma concentrations by liquid chromatography/mass spectrometry. Pharmacokinetic parameters were determined with computer software.
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关键词
Analgesic,Anticonvulsant,Veterinary,Dog,Pharmacology
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