Central corneal thickness effect on GDx VCC parameters

Purpose Evaluate the effect of extreme central corneal thickness in RNFL parameters measured by GDx VCC. Methods A total of 131 eyes of 131 subjects were included divided into 60 control and 71 glaucoma patients. All of the glaucoma eyes had reproducible defects on standard automated perimetry. Central corneal thickness was measured with an ultrasonic pachymeter. ROC curves were plotted in the sample subgroups with exteme pachimetry values (outside mean ± 2SD) and were compared with ROC curves of the subjects in the normal pachimetry range (mean ± 2SD). Results No differences were found in the areas under the ROC curve of the parameter of the GDx VCC in thinnest and thickest subgroups when compared with the mean pachymetry group. Conclusion Central corneal thickness has no influence in RNFL measurements of GDx VCC.