Ethyl 6-[4-(dimethylamino)phenyl]-4-hydroxy-2-oxo-4-(trifluoromethyl)hexahydropyrimidine-5-carboxylate

Acta Crystallographica Section E-structure Reports Online(2010)

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摘要
The title compound, C(16)H(20)F(3)N(3)O(4), was prepared by reaction of 4-(dimethylamino) benzaldehyde, ethyl 4,4,4-trifluoro-3-oxobutanoate and urea. In the title molecule, the pyrimidine ring adopts a half-chair conformation and there is an intramolecular hydrogen bond (O-H center dot center dot center dot O). The crystal structure is stabilized by two types intermolecular hydrogen bonds (N-H center dot center dot center dot O and N-H center dot center dot center dot N).
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bioinformatics,biomedical research
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