Passage Of Dengue Virus Type 4 Vaccine Candidates In Fetal Rhesus Lung Cells Selects Heparin-Sensitive Variants That Result In Loss Of Infectivity And Immunogenicity In Rhesus Macaques
JOURNAL OF VIROLOGY（2009）
Key words
genetic variation,virulence,vaccination,vero cells,potency,serial passage,immune response,infectivity,mutation,dengue
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