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Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists

Phillip M. Cowley,James Baker,Kirsteen I. Buchanan,Ian Carlyle,John K. Clark,Thomas R. Clarkson,Maureen Deehan,Darren Edwards,Yasuko Kiyoi,Iain Martin,Dawn Osbourn,Glenn Walker,Nick Ward,Grant Wishart

Bioorganic & Medicinal Chemistry Letters（2011）

Cited 4|Views25
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Key words
Cannabinoid,CB1,Antagonist,Indole,Pharmacokinetics,CYP3A4,Glucuronidation
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