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Cardio-renal Protection of Riociguat (BAY 63-2521) in Low- and High-Renin Models of Hypertension

BMC pharmacology(2009)

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摘要
Address: 1Department of Nephrology, Charite, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany, 2Center for Cardiovascular Research, Department of Pharmacology and Toxicology, Charite, Campus Mitte, Hessische Str. 3-4, Berlin, Germany, 3Pathology, Research Centre, Bayer HealthCare, Aprather Weg 18a, Wuppertal, Germany, 4Cardiology Research, Bayer HealthCare, Aprather Weg 18a, Wuppertal, Germany, 5Martin-Luther-University, School of Pharmacy, Halle, Germany and 6Department of Pharmacology, University of Cologne, Gleueler Strasse 24, D-50931 Cologne, Germany
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关键词
Pulmonary Hypertension,Glomerulosclerosis,Guanylate Cyclase,Plasma Creatinine,Target Organ Damage
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