Synthesis and structure–activity studies of novel benzocycloheptanone oxazolidinone antibacterial agents

J.V.N. Vara Prasad,Frederick E. Boyer,Lou Chupak,Michael Dermyer,Qizhu Ding,K. Gavardinas,Susan E. Hagen,Michael D. Huband,Wenhua Jiao,Takushi Kaneko,Samarendra N. Maiti,Michael Melnick,Karina Romero,M. Patterson,Xiujuan Wu

Bioorganic & Medicinal Chemistry Letters（2006）

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摘要

We describe a novel class of benzoheptanone derived oxazolidinone antibacterial agents. The synthesis and antibacterial activities with structure variation are described.

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关键词

Oxazolidinones,Antibacterial agents,Gram-negative activity

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