Discovery of thiochroman and chroman derivatives as pure antiestrogens and their structure-activity relationship.
Bioorganic & Medicinal Chemistry(2006)
摘要
In order to develop pure antiestrogens, a series of 7-hydroxy-3-(4-hydroxyphenyl)chroman and 7-hydroxy-3-(4-hydroxyphenyl)thiochroman derivatives with sulfoxide containing side chains at the 4-position were designed, synthesized, and evaluated.
更多查看译文
关键词
Pure antiestrogens,Estrogen,Chroman,Thiochroman
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要