Initial Experiences with a Non-Stented Coronary Sinus Device for the Treatment of Functional Mitral Regurgitation: Results of the PTOLEMY I Feasibility Trial

Background: Recently, several approaches have been developed for percutaneous mitral valve repair. The percutaneous transvenous mitral annuloplasty system (PTMA™, Viacor Inc., Wilmington, USA) is an indirect annuloplasty device deployed within the coronary sinus (CS). Its mechanism is based on reduction of the anterior-posterior diameter of the mitral annulus to decrease mitral regurgitation (MR) by reestablishing leaflet coaptation in functional MR. We report the results of the PTOLEMY I feasibility trial with this non-stented device.