Design and synthesis of novel 7-heterocycle-6-trifluoromethyl-3-oxoquinoxaline-2-carboxylic acids bearing a substituted phenyl group as superior AMPA receptor antagonists with good physicochemical properties.
Bioorganic & Medicinal Chemistry(2006)
Key words
Excitatory amino acid,Competitive AMPA receptor antagonist,3-Oxoquinoxaline-2-carboxylic acid,Cerebral ischemia
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