Rupatadine does not potentiate the CNS depressant effects of lorazepam: randomized, double-blind, crossover, repeated dose, placebo-controlled study.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY(2010)
摘要
Repeated doses of rupatadine (10 mg orally) did not enhance the CNS depressant effects of lorazepam (2 mg orally, single dose) either in objective psychomotor tasks or in subjective evaluations.
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关键词
CNS effects,healthy volunteers,interaction,lorazepam,rupatadine
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