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Expanded Human Cord Blood‐derived Endothelial Progenitor Cells Salvage Infarcted Myocardium in Rats with Acute Myocardial Infarction

Cheng-Heng Hu,Zhi-Ming Li, Zhi-Min Du,Ai-Xia Zhang,Jamal S. Rana,Dong-Hong Liu, Da-Ya Yang,Gui-Fu Wu

Clinical and experimental pharmacology & physiology(2010)

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摘要
1. Cell transplantation has promise as a therapeutic option for restoring impaired heart function after acute myocardial infarction (AMI). However, the optimal cell type to use remains controversial. We investigated the therapeutic efficacy and feasibility of intramyocardial transplantation of human umbilical cord blood‐derived endothelial progenitor cells (hUCB‐EPC) in rats with AMI.
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关键词
endothelial progenitor cells,Endothelial Cell-Lineage Analysis,endothelial cell behavior,Epicardial Progenitors,Extracellular Matrix
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