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Copper-Catalyzed Alkyne Cycloaddition on Electron Deficient Azides Via Tetrazolo[1,5-A]Pyrimidines

Linda I. Nilsson,Anne Ertan,Dirk Weigelt, Jens M. J. Nolsoe

Journal of heterocyclic chemistry（2010）

Cited 13|Views2
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Abstract
Tetrazolo[1,5-a]pyrimidines are capable of serving as masked azides in copper-catalyzed Huisgen cyclization with a variety of terminal alkynes, providing a simple protocol for the generation of novel 4'-substituted 2-(1',2',3'-triazol-l'yl)pyrimidines.
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Key words
Copper-Catalyzed Cycloaddition,Azides and Alkynes,Tetrazoles
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