Polymorphic variations in exon 10 of the luteinizing hormone receptor: functional consequences and associations with breast cancer.

Djura Piersma,Miriam Verhoef-Post,Maxime P Look,André G Uitterlinden,Huibert A P Pols,Els M J J Berns,Axel P N Themmen

Molecular and Cellular Endocrinology（2007）

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摘要

Polymorphic variation of the LHR gene may affect receptor function and accordingly may influence ovarian steroid hormone action, including steroid hormone-dependent clinical outcome.

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关键词

LH receptor,Glycosylation,Breast cancer,Polymorphism

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