Laxanol, A New 2,5-Diaryl-3,4-dihydroxymethyltetrahydrofuran Type Lignan from Justicia Laxa

Jin-Feng Hu,Courtney M. Starks,Eliane Garo,Grayson W. Hough,Stephanie M. Rice,Matt G. Goering,Mark O'Neil-Johnson,Gary R. Eldridge

Journal of chemical research（2008）

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摘要

The unsymmetrical 2,5-diaryl-tetrahydrofuran type lignan, 2-(3′-methoxy-4′-hydroxyphenyl)-3,4-dihydroxymethyl-5-(3″-methoxy-5″-hydroxyphenyl)-tetrahydrofuran, laxanol (1), was obtained from Justicia laxa via high-throughput natural product chemistry methods as a mass-limited sample and its structure was elucidated by capillary scale NMR and HR-/LR-ESIMS analyses.

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关键词

Justicia laxa,2,5-diaryl-tetrahydrofuran type lignan,high-throughput natural product chemistry,CapNMR probe,laxanol

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