Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists.
Bioorganic & Medicinal Chemistry Letters（2009）
摘要
This Letter describes optimization of ghrelin receptor antagonists and inverse agonists starting from a screening hit.
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关键词
Ghrelin,Antagonist,Inverse agonist,Obesity
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