谷歌浏览器插件
订阅小程序
在清言上使用

Effect of sodium selenite supplementation on the levels of Prostacyclin I2 and Thromboxane A2 in human

Thrombosis Research(2007)

引用 8|浏览11
暂无评分
摘要
Selenium is an essential trace element in human health [ 1 Schwarz K. Foltz C.M. Selenium as an integral part of factor 3 against dietary necrotic liver degeneration. J Am Chem Sci. 1957; 79: 3292-3293 Crossref Scopus (1263) Google Scholar , 2 Abdulah R. Miyazaki K. Nakazawa M. Koyama H. Chemical forms of selenium for cancer prevention. J Trace Elem Med Biol. 2005; 19: 141-150 Crossref PubMed Scopus (170) Google Scholar ], an important part of the antioxidant enzymes that protect cells against the effects of free radicals that are produced during the normal oxygen metabolism. The body has developed defenses, such as antioxidants, to control the levels of free radicals, which can damage cells and contribute to the development of some chronic diseases. Several epidemiological studies have shown that serum selenium levels were associated with the development of occlusive vascular disease [ 3 Suadicani P. Hein H.O. Gyntelberg F. Serum selenium concentration and risk of ischaemic heart disease in a prospective cohort study of 3000 males. Atherosclerosis. 1992; 96: 33-42 Abstract Full Text PDF PubMed Scopus (173) Google Scholar , 4 Salonen J.T. Salonen R. Seppanen K. Kantola M. Suntioinen S. Korpela H. Interactions of serum copper, selenium, and low density lipoprotein cholesterol in atherogenesis. Br Med J. 1991; 302: 756-760 Crossref PubMed Scopus (186) Google Scholar , 5 Qu X. Huang K. Deng L. Xu H. Selenium deficiency-induced alterations in the vascular system of the rat. Biol Trace Elem Res. 2000; 75: 119-128 Crossref PubMed Scopus (29) Google Scholar ]. However, conflicting results also have been obtained [ 6 Salvini S. Hennekens C.H. Morris J.S. Willett W.C. Stampfer M.J. Plasma levels of the antioxidant selenium and risk of myocardial infarction among U.S. physicians. Am J Cardiol. 1995; 76: 1218-1221 Abstract Full Text PDF PubMed Scopus (90) Google Scholar , 7 Kardinaal A.F. Kok F.J. Kohlmeier L. Martin-Moreno J.M. Ringstad J. Gomez-Aracena J. et al. Association between toenail selenium and risk of acute myocardial infarction in European men. The EURAMIC Study. European Antioxidant Myocardial Infarction and Breast Cancer. Am J Epidemiol. 1997; 145: 373-379 Crossref PubMed Scopus (76) Google Scholar , 8 Wei W.Q. Abnet C.C. Qiao Y.L. Dawsey S.M. Dong Z.W. Sun X.D. et al. Prospective study of serum selenium concentrations and esophageal and gastric cardia cancer, heart disease, stroke, and total death. Am J Clin Nutr. 2004; 79: 80-85 PubMed Google Scholar ].
更多
查看译文
关键词
sodium selenite
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要