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Associations of Visceral and Subcutaneous Fat Areas with the Prevalence of Metabolic Risk Factor Clustering in 6,292 Japanese Individuals

Diabetes care(2010)SCI 1区

Natl Ctr Global Hlth & Med | Hitachi Ltd | Natl Inst Publ Hlth

Cited 68|Views14
Abstract
OBJECTIVE We examined the relationships of visceral fat area (VFA), subcutaneous fat area, and waist circumference, determined using computed tomography (CT), and BMI with metabolic risk factors in a large Japanese population. RESEARCH DESIGN AND METHODS Study subjects comprised 6,292 men and women who participated in the Hitachi Health Study and received CT examinations in 2007 and 2008. RESULTS Regarding the clustering of metabolic risk factors, the odds ratios (ORs) for the VFA quintiles were 1.0 (ref.), 2.4, 3.4, 5.0, and 9.7 for men and 1.0 (ref.), 1.5, 2.6, 4.6, and 10.0 for women (P < 0.001 for trends in both sexes). For the highest quintiles, the OR for VFA was 1.5 to 2 times higher than those of the other anthropometric indexes in both sexes. CONCLUSIONS We demonstrated a superior performance of VFA to predict the clustering of metabolic risk factors compared with other anthropometric indexes.
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Body Fat Percentage,Body Mass Index
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要点】:研究探讨了内脏脂肪面积(VFA)、皮下脂肪面积和腰围以及体质指数(BMI)与代谢风险因素在日本人群中的关系,结果表明VFA在预测代谢风险因素聚类方面优于其他人体测量指数。

方法】:采用计算机断层扫描(CT)测定 visceral fat area (VFA)、subcutaneous fat area 和腰围,以及BMI,分析这些指标与代谢风险因素之间的关系。

实验】:研究对参与Hitachi健康研究的6,292名男女进行了CT检查(2007年至2008年),通过对比VFA分位数与代谢风险因素聚类的比值比(OR),发现VFA在预测代谢风险因素聚类方面具有更高的准确性。