Donor Simvastatin Treatment is Safe and Might Improve Outcomes after Liver Transplantation: A Randomized Clinical Trial

Slow EEG potentials (Fz, Cz, Pz) and heart rate were recorded during the foreperiod of a reaction task, which involved different levels of discrimination difficulty. A simple reaction task was compared with a selective reaction task where either an easy or a difficult discrimination was required. In general, the terminal amplitude of the CNV was not affected by task difficulty. However, a prolonged negative wave was found when the difficulty of the task was not known to the subject in advance but was indicated by S1. Moreover, the heart-rate deceleration around S2 was more pronounced the more difficult the discrimination required at S2.