Tetrasubstituted Pyridines As Potent and Selective Akt Inhibitors: Reduced Cyp450 and Herg Inhibition of Aminopyridines
Hong Lin,Dennis S. Yamashita,Ren Xie,Jin Zeng,Wenyong Wang,Jack Leber,Igor G. Safonov,Sharad Verma,Mei Li,Louis LaFrance,Joseph Venslavsky,Dennis Takata,Juan I. Luengo,Jason A. Kahana,Shuyun Zhang,Kimberly A. Robell,Dana Levy, Rakesh Kumar,Anthony E. Choudhry,Michael Schaber,Zhihong Lai,Barry S. Brown,Brian T. Donovan,Elisabeth A. Minthorn,Kristin K. Brown,Dirk A. Heerding Bioorganic & medicinal chemistry letters(2010)
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AKT kinase inhibitors,Aminopyridines
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