Inhibition of γ-secretase by the CK1 inhibitor IC261 does not depend on CK1δ

Bioorganic & Medicinal Chemistry Letters(2010)

引用 17|浏览8
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摘要
Structural similarity of IC261 and the GSM of the Sulindac-series (2, 4).
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关键词
Alzheimer’s disease,γ-Secretase,Casein kinase 1,Amyloid b secretion
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