Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP.

Marcos González-López,Kate Welsh,Darren Finlay,Robert J Ardecky,Santhi Reddy Ganji,Ying Su,Hongbin Yuan,Peter Teriete,Peter D Mace,Stefan J Riedl,Kristiina Vuori,John C Reed,Nicholas D P Cosford

Bioorganic & Medicinal Chemistry Letters（2011）

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关键词

Apoptosis,XIAP,Monovalent Smac mimietics,Probe compounds

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