INFLUENCE OF HOST GENOTYPE ON PROGRESSION TO ACQUIRED IMMUNODEFICIENCY SYNDROME AMONG CHILDREN INFECTED WITH HUMAN IMMUNODEFICIENCY VIRUS TYPE 1

The specific factors that determine the clinical course in individual patients with HIV infection are yet to be precisely defined. Variable virus subtypes are likely to produce different clinical pictures. This article documents that host factors, such as HLA genotype, are also important in clinical outcome. The relative importance of host versus viral characteristics is as yet undetermined.