Generation of Ips Cell Line (Icgi040-A) from Skin Fibroblasts of a Patient with Ring Small Supernumerary Marker Chromosome 4.

M. M. Gridina,A. R. Nurislamov,J. M. Minina,M. E. Lopatkina,G. V. Drozdov,L. I. Minaycheva,E. O. Belyaeva,T. V. Nikitina,A. A. Kashevarova,T. V. Karamysheva,N. B. Rubtsov,O. L. Serov

Stem cell research（2022）

引用 19|浏览9

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摘要

Human induced pluripotent stem cell (iPSC) line, ICGi040-A, was obtained from skin fibroblasts derived from a male patient with mosaic ring small supernumerary marker chromosome 4 (sSMS(4)) and infertility. ICGi040-A cells have karyotype 47,XY,+r(4) in 97% of cells and express a set of pluripotent markers, as well as are able to differentiate in vitro into derivatives of all three embryonic germ layers.

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关键词

Bromhexine,Metabolites,RRLC-MS/MS,Quantification,Pharmacokinetics,Human plasma

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