Network of Coordinated Substitutions in the Hepatitis B Virus Polymerase

D. S. Campo,Z. Dimitrova,J. Lara,M. Purdy, H. Thai,S. Ramachandran,L. Ganova-Raeva,X. Zhai,J. C. Forbi,C. G. Teo,Y. Khudyakov

2011 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)（2011）

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关键词

HBV polymerase,HBV genome,intrinsically unstructured domain,reverse-transcriptase domain,spacer domain,Bayesian network,central role,crucial functional role,epistatic network,highest network centrality,Hepatitis B virus polymerase

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