Isshiki Yusuke - Department of Hematology, Chiba University Hospital

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Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma

Efrat Shema,Ofir Griess,Noa Furth,Nofar Harpaz, Nicoletta Di Bernardo,Tomer Meir Salame,Bareket Dassa,Ioannis Karagiannidis,Yusuke Isshiki,Menachem Gross,Ari M Melnick,Wendy Beguelin,Guy Ron

biorxiv（2024）

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Abstract PO-040: Mechanisms of Action of Immune Checkpoint Blockade Therapy in EZH2/Bcl2-mutant B-cell Lymphomas

Alexey V. Sarapulov,Serganova Inna,Ryan Bucktrout,Yusuke Isshiki,Anthony Santella, Marc-Anthony Rodriguez,Sanjukta Chakraborty, Solene Brunschvig,Santosha A. Vardhana,Claudio Tripodo,Ari Melnick,Wendy Béguelin,Roberta Zappasodi

Blood cancer discoveryno. 3_Supplement (2024): PO-040

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EZH2 Inhibitors Enhance CART Cell Quality, Efficacy, in Vivo Homing, Tumor Cell Binding and Killing of Fully Syngeneic Primary B Cell Lymphomas, As Well As Reprogramming Lymphoma Cells to a Highly Immunogenic and T Cell Adherent Phenotype

Yusuke Isshiki,Patrizia Porazzi,Xi Chen,Matthew Teater,Ioannis Karagiannidis, Henna S. Nam,Ari M. Melnick,Marco Ruella, Wendy Baguelin

BLOOD (2023)

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Development of Syngeneic Murine Cell Lines of Germinal Center-Derived B-Cell Lymphomas

Henna S. Nam,Yusuke Isshiki,Min Xia, Sanket Shah,Meng Li,Ioannis Karagiannidis,Matthew Teater,Ari M. Melnick, Wendy Baguelin

BLOOD (2023)

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Future Prospects for Targeting the Epigenome in Lymphomas

Yusuke Isshiki,Ari Melnick

Precision Cancer Therapies, Volume 1 ‐ Targeting Oncogenic Drivers and Signaling Pathways in Lymphoid Malignanciespp.236-248, (2023)

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Qpctl Inhibition, by Targeting the Inflammatory Tumor Microenvironment, Constitutes a Novel Therapeutic Approach for Diffuse Large B-Cell Lymphoma

Nicolas Di Siervi, Jasper Mullender,Maria Victoria Revuelta,Nahuel Zamponi,Eloisi Caldas-Lopes,Yusuke Isshiki, Wendy Baguelin, Marcel Scheepstra,Bastiaan Evers,Jens Wuerthner,Leandro Cerchietti

BLOOD (2023)

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[Identification of Transcriptional Features and Surface Markers of Plasma Cell Clones in POEMS Syndrome by Single-Cell RNA Sequencing]

Yusuke Isshiki,Motohiko Oshima,Naoya Mimura,Emiko Sakaida,Atsushi Iwama

PubMedno. 7 (2023): 581-585

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Enhancing T‐cell Responses to GCB‐like Lymphomas with Immune‐checkpoint‐blockade‐based Therapies

I. Serganova,R. Bucktrout,Y. Isshiki, A. Sarapulov, A. Santella, M. Rodriguez,S. Chakraborty, S. Brunschvig,D. Qualls,S. Vardhana, A. Lesokhin,A. Melnick,W. Beguelin,R. Zappasodi

Hematological Oncologyno. S2 (2023): 280-280

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