基本信息
浏览量:1
职业迁徙
个人简介
Research Areas
Dr. Gao’s research program lies at the interface of chemical biology and biomolecular engineering with primary focus on small- and macro-molecule discovery and their applications to human health, agriculture, and energy. Natural products from microorganisms of diverse origins have played an extremely important role historically in drug discovery. Recent advances in human microbiome research have expanded our understanding of interactions between microbes and hosts related to human health. This unique microbial community also provides a golden opportunity for the discovery of new therapeutics. One of her main research is microbiome-based natural product discovery and engineering, and moreover, to develop enzymes involved in the natural product biosynthesis as powerful biocatalysts for difficult chemical reactions in the pharmaceutical and biotechnology industries. The recently discovered microbial ribonucleoprotein, CRISPR/Cas9, in complex with a single guide RNA, has been extensively applied to mediate genome—editing both in vitro and in vivo. Human genetic diseases were previously recognized to be untreatable until recent advances in genome-editing research, which have been revolutionizing medicine for treating human genetic diseases. Another main research interest of her group is to discover and develop advanced genome-editing agents and delivery systems and apply these genome-editing tools as next-generation therapeutics to clinical treatment of human genetic diseases.
Dr. Gao’s research program lies at the interface of chemical biology and biomolecular engineering with primary focus on small- and macro-molecule discovery and their applications to human health, agriculture, and energy. Natural products from microorganisms of diverse origins have played an extremely important role historically in drug discovery. Recent advances in human microbiome research have expanded our understanding of interactions between microbes and hosts related to human health. This unique microbial community also provides a golden opportunity for the discovery of new therapeutics. One of her main research is microbiome-based natural product discovery and engineering, and moreover, to develop enzymes involved in the natural product biosynthesis as powerful biocatalysts for difficult chemical reactions in the pharmaceutical and biotechnology industries. The recently discovered microbial ribonucleoprotein, CRISPR/Cas9, in complex with a single guide RNA, has been extensively applied to mediate genome—editing both in vitro and in vivo. Human genetic diseases were previously recognized to be untreatable until recent advances in genome-editing research, which have been revolutionizing medicine for treating human genetic diseases. Another main research interest of her group is to discover and develop advanced genome-editing agents and delivery systems and apply these genome-editing tools as next-generation therapeutics to clinical treatment of human genetic diseases.
研究兴趣
论文共 71 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Bo Gao,Yi Jiang,Mingyu Han,Xiaowen Ji,Dejun Zhang,Lihua Wu,Xue Gao,Shasha Huang,Chaoyue Zhao,Yu Su,Suyan Yang,Xin Zhang,Na Liu, Lu Han, Lihai Wang, Lina Ren,Jinyuan Yang,Jian Wu,Yongyi Yuan,Pu Dai
The Journal of molecular diagnostics/The journal of molecular diagnostics (2024)
Current opinion in biotechnology (2024): 103071-103071
BMC medical genomicsno. 1 (2024): 32-32
Bo Gao, Yi Jiang,Mingyu Han, Xiaowen Ji,Dejun Zhang,Xue Gao, Shasha Huang,Chaoyue Zhao,Yu Su, Suyan Yang,Xin Zhang,Na Liu, Lu Han, Lihai Wang, Lina Ren, Jinyuan Yang,Jian Wu,Yongyi Yuan,Pu Dai
JOURNAL OF MOLECULAR DIAGNOSTICSno. 7 (2024): 638-651
Lab on a chipno. 17 (2023): 3862-3873
Zhengyan Weng,Zheng You,Huijie Li,Guangfu Wu,Yang Song,He Sun, Ava Fradlin, Camille Neal-Harris,Mengshi Lin,Xue Gao,Yi Zhang
ACS SENSORSno. 4 (2023): 1489-1499
Synthetic biology (Oxford, England)no. 1 (2023): ysad017-ysad017
Chemical reviewsno. 12 (2023): 7782-7853
加载更多
作者统计
#Papers: 71
#Citation: 3488
H-Index: 22
G-Index: 55
Sociability: 6
Diversity: 3
Activity: 97
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn