Xin Chen - University of North Carolina at Chapel Hill

基本信息

Career Trajectory

Bio

Xin Chen obtained his Ph. D. degree in organic chemistry from Lanzhou University in 1993. He was Associate Professor at Department of Chemistry, Tsinghua University from 1995-1997, Assistant Research Professor at Department of Chemistry, Duke University from 2005-2010, and became full professor at School of pharmacy, Changzhou University since 2010. His research interests are novel GPCR modulators, drug discovery for treating infection and tumors, as well as synthesis of small molecules with important biological activities.

Research Interests

Papers共 177 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Visible-Light-Mediated Cyclopropanation Reactions of 3-Diazooxindoles with Olefins

Zhuangzhuang Mu, Haochi Xie, Shundong Gan, Hujin Li, Yanan Hou, Mingcheng Qian,Shuai Zhao,Xin Chen

TETRAHEDRON (2024)

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Figure S5 from Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

Huijuan Wang,Jiaxin Chen,Xiaoyu Chen, Yingqiang Liu,Jiawei Wang,Qing Meng,Huogang Wang, Ying He, Yujia Song, Jingyun Li,Zhenyu Ju, Peng Xiao, Junbin Qian, Zhangfa Song

crossref（2024）

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Chemotherapy-Induced Peripheral Neuropathy: A Recent Update on Pathophysiology and Treatment

Marina Mattar, Florence Umutoni, Marwa A Hassan, M Wambui Wamburu, Reagan Turner, James S Patton,Xin Chen,Wei Lei

Life (Basel, Switzerland)no. 8 (2024)

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Quantitative Proteomic Mass Spectrometry of Protein Kinases to Determine Dynamic Heterogeneity of the Human Kinome

Michael P East,Robert W Sprung,Denis O Okumu, J Felix Olivares-Quintero,Chinmaya U Joisa,Xin Chen,Qiang Zhang,Petra Erdmann-Gilmore,Yiling Mi,Noah Sciaky,James P Malone,Sonam Bhatia,Ian C McCabe, Yi Xu, Matthew D Sutcliffe,Jingqin Luo,Patricia A Spears,Charles M Perou,H Shelton Earp,Lisa A Carey, Jen,David L Spector,Shawn M Gomez, Philip M Spanheimer, R Reid Townsend,Gary L Johnson

bioRxiv the preprint server for biology (2024)

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Structure Optimization of Cmpd-15 As Negative Allosteric Modulators for the Β2-Adrenergic Receptor

Xue Guo,Zhijie Luo, Ying Qi, Xiaoyuan Hei,Xin Zhang, Xuli Cao,Mingcheng Qian,Shuai Zhao, Yanan Hou,Xin Chen

BIOORGANIC & MEDICINAL CHEMISTRY (2024)

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Supplementary Data, Table S1-3 from Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

Huijuan Wang,Jiaxin Chen,Xiaoyu Chen, Yingqiang Liu, Jiawei Wang,Qing Meng,Huogang Wang, Ying He, Yujia Song, Jingyun Li,Zhenyu Ju, Peng Xiao, Junbin Qian, Zhangfa Song

crossref（2024）

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Visible-Light-Mediated O–H Functionalization Reactions of Acetylenic Alcohols with 3-Diazooxindoles: Facile Access to Spirooxindole-Fused Oxacycles

Liqin Xu, Jing Wang, Hujin Li, Haochi Xie,Mingcheng Qian, Yanan Hou,Shuai Zhao,Xin Chen

TETRAHEDRON (2024)

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Allosteric Inhibition of the Β2-Adrenergic Receptor: Design and Synthesis of Cmpd-15 Analogs

Kexin Ye, Qing Li,Zhijie Luo, Qianchen Lu,Xue Rui, Yan Li, Jie Jin,Chenchen Jing, Meiling Hong,Mingcheng Qian,Shuai Zhao, Yanan Hou,Xin Chen

Chemistry & biodiversitypp.e202401420-e202401420, (2024)

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Create Artilysins from a Recombinant Library to Serve As Bactericidal and Antibiofilm Agents Targeting Pseudomonas Aeruginosa

Ting Zeng, Shuang Liu, Peixuan Zou, Xin Yao,Qiexin Chen,Long Wei,Qiantao Wang,Chun Zhang,Yongxiang Zheng,Rong Yu

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2024)

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Figure S8 from Cancer-Associated Fibroblasts Expressing Sulfatase 1 Facilitate VEGFA-Dependent Microenvironmental Remodeling to Support Colorectal Cancer

Huijuan Wang,Jiaxin Chen,Xiaoyu Chen, Yingqiang Liu,Jiawei Wang,Qing Meng,Huogang Wang, Ying He, Yujia Song, Jingyun Li,Zhenyu Ju, Peng Xiao, Junbin Qian, Zhangfa Song

crossref（2024）

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