Dr. Hsiao directs the Public Health Bioinformatics Group, an interdisciplinary group of researchers interested in solving practical public health and animal health problems through a One Health lens. The team combines knowledge engineering techniques and bioinformatics tool development to improve data sharing and integrated analysis in public health. Dr. Hsiao’s team developed several ontologies used to consistently describe health knowledge and data. These include the Genomic Epidemiology Ontology (GenEpiO) to describe genomics-based infectious disease surveillance data and the Food Ontology (FoodOn), a comprehensive set of vocabularies to describe various aspects of “food” ranging from food processing, food products, food consumers, to diet, linking together agricultural and nutritional data. FoodOn is currently being adopted by the USDA FoodData Central. His team is also developing ontology-driven text-mining tools to improve the extraction and re-use of biological data following FAIR principles.