基本信息
views: 78
Career Trajectory
Bio
Interests
Where does the nervous system come from in the embryo? How does it grow to the right size and shape? How do stem cells turn into more committed neuronal progenitors and how do these cells know when to leave the cycle and differentiate into neural and glial progenitors? Once born, how do these precursors differentiate? How do they choose a particular cell type to become amongst a myriad of possible fates, and by what cellular mechanisms do these cells become properly polarised, branched, and integrated into the retinal circuitry? What mechanisms allow retinal ganglion cells to send out long axons that forge pathways to their targets in the brain, and recognise specific cells within these targets? These were the main questions that my laboratory investigated using the visual systems of Xenopus and zebrafish because of their embryological, molecular and genetic accessibility to experimentation, combined with the possibility of in vivo time-lapse imaging.
Where does the nervous system come from in the embryo? How does it grow to the right size and shape? How do stem cells turn into more committed neuronal progenitors and how do these cells know when to leave the cycle and differentiate into neural and glial progenitors? Once born, how do these precursors differentiate? How do they choose a particular cell type to become amongst a myriad of possible fates, and by what cellular mechanisms do these cells become properly polarised, branched, and integrated into the retinal circuitry? What mechanisms allow retinal ganglion cells to send out long axons that forge pathways to their targets in the brain, and recognise specific cells within these targets? These were the main questions that my laboratory investigated using the visual systems of Xenopus and zebrafish because of their embryological, molecular and genetic accessibility to experimentation, combined with the possibility of in vivo time-lapse imaging.
Research Interests
Papers共 288 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Sherry Everett Jones,Nancy D. Brener,Barbara Queen, Molly Hershey-Arista,William Harris,J. Michael Underwood
Journal of school healthno. 5 (2024): 395-405
Sherry Everett Jones,Nancy D. Brener,Barbara Queen, Molly Hershey-Arista,William A. Harris,Jonetta J. Mpofu,J. Michael Underwood
American journal of health promotion (2024)
openalex(2023)
Neurosurgery/Neurosurgery onlineno. 4 (2023): 666-678
Jonetta J Mpofu,J Michael Underwood,Jemekia E Thornton,Nancy D Brener,Adriana Rico,Greta Kilmer,William A Harris,Michelle Leon-Nguyen,David Chyen,Connie Lim,Cecily K Mbaka,Jennifer Smith-Grant,Lisa Whittle,Sherry Everett Jones,Kathleen H Krause,Jingjing Li,Shari L Shanklin, Izzy McKinnon, Loredona Arrey,Barbara E Queen,Alice M Roberts
MMWR supplementsno. 1 (2023): 1-12
JOURNAL OF NEUROSURGERYno. 5 (2022)
Cited0Views0Bibtex
0
0
Load More
Author Statistics
#Papers: 286
#Citation: 25826
H-Index: 82
G-Index: 158
Sociability: 7
Diversity: 0
Activity: 1
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn