In 1986, Dr. Friedman began collaborative work with Dr. Frank Bova, which led to the development of the University of Florida radiosurgery system. This system was subsequently patented by the University of Florida and licensed to Philips, then Sofamor-Danek, then Varian. The commercial version of the system has become one of the most popular radiosurgical systems worldwide. Drs. Friedman and Bova received the 1990 UF College of Medicine Clinical Research Prize in recognition of this accomplishment. Dr. Friedman is the leader of a multidisciplinary radiosurgery team which has treated over 5000 patients, published more than170 papers and chapters, produced many international meetings, and educated hundreds of visiting physicians. Drs. Bova and Friedman received NIH R01 funding to support their continuing research efforts.