Wiebke Mobius - Max Planck Institute for Multidisciplinary Sciences

基本信息

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Bio

We are interested in understanding the biology oligodendrocytes which are the myelinating glia cells in the central nervous system. To study this we use conditional mouse mutants or mouse disease models and apply imaging techniques such as 3D electron microscopy or localization techniques using immunogold staining. Currently we are investigating the maintenance of CNS myelin internodes and aspects of axonal pathologies in myelin mutants.

Research Interests

Papers共 178 篇Author StatisticsCo-AuthorSimilar Experts

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Cargo-specific Effects of Hypoxia on Clathrin-Mediated Trafficking

Gijsbert J. van Belle,Anke Zieseniss, Doris Heidenreich, Maxime Olmos, Asia Zhuikova,Wiebke Möbius,Maarten W. Paul,Dörthe M. Katschinski

Pflügers Archiv - European Journal of Physiology (2024)

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Plasma Extracellular Vesicle Tau and TDP-43 As Diagnostic Biomarkers in FTD and ALS

Madhurima Chatterjee,Selcuk Ozdemir, Christian Fritz,Wiebke Mobius,Luca Kleineidam,Eckhard Mandelkow,Jacek Biernat, Cem Dogdu,Oliver Peters,Nicoleta Carmen Cosma,Xiao Wang, Luisa-Sophia Schneider,Josef Priller,Eike Spruth,Andrea A. Kuhn,Patricia Krause,Thomas Klockgether,Ina R. Vogt,Okka Kimmich,Annika Spottke,Daniel C. Hoffmann,Klaus Fliessbach,Carolin Miklitz,Cornelia McCormick,Patrick Weydt,Bjorn Falkenburger,Moritz Brandt,Rene Guenther,Elisabeth Dinter,Jens Wiltfang,Niels Hansen,Mathias Bahr,Inga Zerr,Agnes Floel,Peter J. Nestor,Emrah Duzel,Wenzel Glanz,Enise Incesoy,Katharina Burger,Daniel Janowitz,Robert Perneczky,Boris S. Rauchmann,Franziska Hopfner,Olivia Wagemann,Johannes Levin,Stefan Teipel,Ingo Kilimann,Doreen Goerss,Johannes Prudlo,Thomas Gasser,Kathrin Brockmann,David Mengel,Milan Zimmermann,Matthis Synofzik,Carlo Wilke, Judit Selma-Gonzalez,Janina Turon-Sans,Miguel Angel Santos-Santos,Daniel Alcolea,Sara Rubio-Guerra,Juan Fortea,Alvaro Carbayo,Alberto Lleo,Ricardo Rojas-Garcia,Ignacio Illan-Gala,Michael Wagner,Ingo Frommann,Sandra Roeske, Lucas Bertram,Michael T. Heneka,Frederic Brosseron,Alfredo Ramirez,Matthias Schmid,Rudi Beschorner,Annett Halle,Jochen Herms,Manuela Neumann,Nicolas R. Barthelemy,Randall J. Bateman,Patrizia Rizzu,Peter Heutink,Oriol Dols-Icardo,Guenter Hoeglinger,Andreas Hermann,Anja Schneider

NATURE MEDICINEno. 6 (2024): 1771-+

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High‐Load Core@Shell Nanocarriers with Irinotecan and 5‐fluorouracil for Combination Chemotherapy in Colorectal Cancer

Silke Notter, Dolma Choezom, Titus Griebel,Fernanda Ramos-Gomes,Wiebke Moebius, Tiago De Oliveira,Lena-Christin Conradi,Frauke Alves,Claus Feldmann

SMALL SCIENCE (2024)

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Oligodendrocyte–axon Metabolic Coupling is Mediated by Extracellular K+ and Maintains Axonal Health

Zoe J. Looser, Zainab Faik,Luca Ravotto,Henri S. Zanker,Ramona B. Jung,Hauke B. Werner,Torben Ruhwedel,Wiebke Möbius,Dwight E. Bergles,L. Felipe Barros,Klaus-Armin Nave,Bruno Weber,Aiman S. Saab

NATURE NEUROSCIENCEno. 3 (2024)

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Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy

Nora Josefine Paulke, Carolin Fleischhacker, Justus B. Wegener, Gabriel C. Riedemann,Constantin Cretu, Mufassra Mushtaq, Nina Zaremba,Wiebke Moebius, Yannik Zuehlke, Jasper Wedemeyer, Lorenz Liebmann, Anastasiia A. Gorshkova,Daniel Kownatzki-Danger,Eva Wagner,Tobias Kohl,Carolin Wichmann,Olaf Jahn,Henning Urlaub,Karl Toischer,Gerd Hasenfuss,Tobias Moser,Julia Preobraschenski,Christof Lenz,Eva A. Rog-Zielinska,Stephan E. Lehnart,Soeren Brandenburg

CIRCULATION RESEARCH（2024）

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Axon Demyelination and Degeneration in a Zebrafish Spastizin Model of Hereditary Spastic Paraplegia

Vranda Garg, Selina André, Luisa Heyer, Gudrun Kracht,Torben Ruhwedel,Patricia Scholz,Till Ischebeck,Hauke B Werner, Christian Dullin,Jacob Engelmann,Wiebke Möbius,Martin C Göpfert,Roland Dosch,Bart R H Geurten

Open biologyno. 11 (2024): 240100-240100

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Myelinated Peripheral Axons Are More Vulnerable to Mechanical Trauma in a Model of Enlarged Axonal Diameters

Vasiliki-Ilya Gargareta,Stefan A. Berghoff,Doris Krauter,Sophie Huemmert,Katy L. H. Marshall-Phelps,Wiebke Moebius,Klaus-Armin Nave,Robert Fledrich,Hauke B. Werner,Maria A. Eichel-Vogel

Glia（2024）

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Oligodendrocytes Produce Amyloid-Β and Contribute to Plaque Formation Alongside Neurons in Alzheimer’s Disease Model Mice

Andrew Octavian Sasmita,Constanze Depp,Taisiia Nazarenko,Ting Sun,Sophie B. Siems, Erinne Cherisse Ong, Yakum B. Nkeh, Carolin Boehler, Xuan Yu, Bastian Bues, Lisa Evangelista, Shuying Mao,Barbara Morgado, Zoe Wu,Torben Ruhwedel,Swati Subramanian, Friederike Boerensen,Katharina Overhoff,Lena Spieth,Stefan A. Berghoff,Katherine Rose Sadleir,Robert Vassar, Simone Eggert,Sandra Goebbels,Takashi Saito,Takaomi Saido,Gesine Saher,Wiebke Moebius,Goncalo Castelo-Branco,Hans-Wolfgang Klafki,Oliver Wirths,Jens Wiltfang,Sarah Jaekel,Riqiang Yan,Klaus-Armin Nave

NATURE NEUROSCIENCEno. 9 (2024)

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Defective Mitochondrial COX1 Translation Due to Loss of COX14 Function Triggers ROS-induced Inflammation in Mouse Liver

Abhishek Aich,Angela Boshnakovska,Steffen Witte, Tanja Gall, Kerstin Unthan-Fechner,Roya Yousefi,Arpita Chowdhury, Drishan Dahal,Aditi Methi, Svenja Kaufmann,Ivan Silbern,Jan Prochazka,Zuzana Nichtova,Marcela Palkova, Miles Raishbrook,Gizela Koubkova,Radislav Sedlacek,Simon E. Troeder,Branko Zevnik,Dietmar Riedel,Susann Michanski,Wiebke Moebius,Philipp Stroebel,Christian Luechtenborg,Patrick Giavalisco,Henning Urlaub,Andre Fischer,Britta Bruegger,Stefan Jakobs,Peter Rehling

Nature Communicationsno. 1 (2024)

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