Professor Wurst’s research is focused on generating and analyzing genetic mouse models and human cellular models of neuropsychiatric diseases (neurodegeneration and depression). These models provide fundamental insights into the underlying molecular mechanisms behind the pathogenesis of such diseases, and these in turn serve as the basis for the development of new and innovative therapeutic approaches. Among other things, Professor Wurst is also currently investigating the possibility of applying new “Genome Editing” Technologies (e.g. CRISPR/Cas System) for the treatment of these diseases.