Professional Interests:
A) Mitigation of radiation injury in the brain using pharmacological interventions and conformal avoidance techniques to rescue and spare stem cell compartments.
B) Use of nonlinear systems theory to predict and eventually control (i.e. stabilize) the breathing pattern and hence the tumor motion based on fast intratreatment fraction imaging. Develop real-time adaptive RT techniques that can correct for changes on the fly.
C) Further development of advanced dosimetry systems for spot scanning proton dosimetry and further development of proton CT stopping power images for daily Bragg Peak prediction prior to the delivery of IMPT.
D) Use of functional imaging to define and characterize high-risk volumes for risk adaptive radiotherapy.
E) Use of functional imaging to assess treatment response of tumors to therapy.
F) Development of decision support systems for adaptive radiation therapy.