基本信息
views: 135
Career Trajectory
Bio
Firstly he used his expertise in gene targeting in the mouse to study signal transduction in lymphocytes, exploring the roles of signaling molecules such as Syk, Vav1, Rac1 and Rac2 in B and T cell development, activation and survival.
Secondly, in close collaboration with Elizabeth Fisher, he used his knowledge of genetic manipulation of mice to generate a novel model of Down Syndrome, the Tc1 mouse strain. This strain of mice carries a freely segregating copy of human chromosome 21 and has a number of phenotypes resembling the human condition, including defects in learning and memory, cardiac and craniofacial defects.
Secondly, in close collaboration with Elizabeth Fisher, he used his knowledge of genetic manipulation of mice to generate a novel model of Down Syndrome, the Tc1 mouse strain. This strain of mice carries a freely segregating copy of human chromosome 21 and has a number of phenotypes resembling the human condition, including defects in learning and memory, cardiac and craniofacial defects.
Research Interests
Papers共 265 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Pishan Chang,Marta Pérez-González, Jessica Constable, Daniel Bush, Karen Cleverley,Victor L J Tybulewicz,Elizabeth M C Fisher,Matthew C Walker
The Neuroscientist a review journal bringing neurobiology, neurology and psychiatrypp.10738584241271414-10738584241271414, (2024)
Frontiers in Behavioral Neuroscience (2024)
Eva Lana-Elola,Rifdat Aoidi, Miriam Llorian,Dorota Gibbins, Callan Buechsenschuetz,Claudio Bussi,Helen Flynn,Tegan Gilmore,Sheona Watson-Scales, Marie Haugsten Hansen,Darryl Hayward,Ok-Ryul Song,Veronique Brault,Yann Herault,Emmanuel Deau,Laurent Meijer,Ambrosius P. Snijders,Maximiliano G. Gutierrez,Elizabeth M. C. Fisher,Victor L. J. Tybulewicz
SCIENCE TRANSLATIONAL MEDICINEno. 731 (2024)
Paige Mumford,Clíona Farrell, Gareth Banks,Dervis A. Salih,Victor L. J. Tybulewicz,Elizabeth Fisher,Frances K. Wiseman
Alzheimer's & dementiano. S13 (2023)
Leonard L. de Boer,Lesley Vanes,Serena Melgrati,Joshua Biggs O'May,Darryl Hayward, Paul C. Driscoll,Jason Day,Alexander Griffiths, Renata Magueta,Alexander Morrell, James I. MacRae,Robert Kochl,Victor L. J. Tybulewicz
Phillip M. Muza, Marta Pérez, Noy S, Miyu Kurosawa,Loukia Katsouri,Victor L. J. Tybulewicz,Elizabeth Fisher,Steven J. West
BMC research notesno. 1 (2023)
Joshua Biggs O’May,Lesley Vanes,Leonard L. de Boer,Harald Hartweger, Simone Kunzelmann,Darryl Hayward, Miriam Llorian, David A. Lewis,Robert Köchl,Victor L. J. Tybulewicz
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Kourtney Sloan,Jared Thomas,Matthew Blackwell, Deanna Voisard,Eva Lana-Elola,Sheona Watson-Scales, Daniel L. Roper,Joseph M. Wallace,Elizabeth M. C. Fisher,Victor L. J. Tybulewicz,Randall J. Roper
NEUROBIOLOGY OF DISEASE (2023)
Load More
Author Statistics
#Papers: 265
#Citation: 24644
H-Index: 79
G-Index: 155
Sociability: 7
Diversity: 0
Activity: 1
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn